Chronic Pancreatitis
June 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Earlier surgery improves outcomes from painful chronic pancreatitis.
Authors:Ke N, Jia D, Huang W, Nunes QM, Windsor JA, Liu X, Sutton R
Institution:Department of Pancreatic Surgery. China Hospital, Sichuan University, Chengdu, China. Hospital, University of Liverpool, Liverpool, UK. Hospital, University of Liverpool, Liverpool, UK.
Journal:Medicine (Baltimore). 2018 May;97(19):e0651. doi: 10.1097/MD.0000000000010651.

2:Pain Control, Glucose Control, and Quality of Life in Patients With Chronic Pancreatitis After Total Pancreatectomy With Islet Autotransplantation: A Preliminary Report.
Authors:Solomina J, Golebiewska J, Kijek MR, Kotukhov A, Bachul PJ, Basto L, Golab K, Konsur E, Cieply K, Fillman N, Wang LJ, Thomas CC, Philipson LH, Tibudan M, Debska-Slizien A, Fung J, Gelrud A, Matthews JB, Witkowski P
Institution:Department of Surgery, University of Chicago, Chicago, USA. Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland. University of Gdansk, Gdansk, Poland. pwitkowski@surgery.bsd.uchicago.edu.
Journal:Transplant Proc. 2017 Dec;49(10):2333-2339. doi: 10.1016/j.transproceed.2017.10.010.

3:Prognostic factors of response to endoscopic treatment in painful chronic pancreatitis.
Authors:Tantau A, Mandrutiu A, Leucuta DC, Ciobanu L, Tantau M
Institution:Department of Internal Medicine and Gastroenterology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca City, 400012 Cluj, Romania. Cluj-Napoca City, 400132 Cluj, Romania. office@doctortantau.ro. Medicine and Pharmacy, Cluj-Napoca City, 400012 Cluj, Romania. University of Medicine and Pharmacy, Cluj-Napoca City, 400012 Cluj, Romania. University of Medicine and Pharmacy, Cluj-Napoca City, 400012 Cluj, Romania.
Journal:World J Gastroenterol. 2017 Oct 7;23(37):6884-6893. doi: 10.3748/wjg.v23.i37.6884.

4:Diagnosing Chronic Pancreatitis: Comparison and Evaluation of Different Diagnostic Tools.
Authors:Issa Y, van Santvoort HC, van Dieren S, Besselink MG, Boermeester MA, Ahmed Ali U
Institution:From the *Department of Surgery, Academic Medical Center, Amsterdam; daggerDepartment of Surgery, St Antonius Hospital, Nieuwegein; and double daggerDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Journal:Pancreas. 2017 Oct;46(9):1158-1164. doi: 10.1097/MPA.0000000000000903.

5:Chronic pancreatitis.
Authors:Kleeff J, Whitcomb DC, Shimosegawa T, Esposito I, Lerch MM, Gress T, Mayerle J, Drewes AM, Rebours V, Akisik F, Munoz JED, Neoptolemos JP
Institution:Department of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), Germany. Medicine, University of Liverpool, Liverpool, UK. of Pittsburgh &UPMC, Pittsburgh, Pennsylvania, USA. Sendai, Japan. Dusseldorf, Germany. Marburg, Germany. University Munich, Munich, Germany. &Hepatology, Clinical Institute, Aalborg University Hospital, Aalborg, Denmark. Medicine, Indianapolis, Indiana, USA. University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Journal:Nat Rev Dis Primers. 2017 Sep 7;3:17060. doi: 10.1038/nrdp.2017.60.

6:MRI assessed pancreatic morphology and exocrine function are associated with disease burden in chronic pancreatitis.
Authors:Madzak A, Olesen SS, Lykke Poulsen J, Bolvig Mark E, Mohr Drewes A, Frokjaer JB
Institution:aDepartment of Radiology, Imaging Research Unit & Mech-Sense bDepartment of Gastroenterology & Hepatology, Centre for Pancreatic Diseases & Mech-Sense, Aalborg University Hospital cDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Journal:Eur J Gastroenterol Hepatol. 2017 Nov;29(11):1269-1275. doi: 10.1097/MEG.0000000000000955.

7:The Surgeon's Role in Treating Chronic Pancreatitis and Incidentally Discovered Pancreatic Lesions.
Authors:Dhar VK, Xia BT, Ahmad SA
Institution:Division of Surgical Oncology, Department of Surgery, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, ML 0558, SRU Room 1466, Cincinnati, OH, 45219, USA. ahmadsy@uc.edu.
Journal:J Gastrointest Surg. 2017 Dec;21(12):2110-2118. doi: 10.1007/s11605-017-3534-7. Epub 2017 Aug 14.

8:Risk of Pancreatic Cancer After a Primary Episode of Acute Pancreatitis.
Authors:Rijkers AP, Bakker OJ, Ahmed Ali U, Hagenaars JCJP, van Santvoort HC, Besselink MG, Bollen TL, van Eijck CH
Institution:From the *Department of Surgery, Erasmus MC, University Medical Center, Rotterdam; daggerDepartment of Surgery, University Medical Center, Utrecht; double daggerDepartment of Surgery, Maasstad Hospital, Rotterdam; section signDepartment of Surgery, Academic Medical Center, Amsterdam; and parallelDepartment of Radiology, St Antonius Hospital, Nieuwegein, The Netherlands.
Journal:Pancreas. 2017 Sep;46(8):1018-1022. doi: 10.1097/MPA.0000000000000879.

9:Chronic pancreatitis.
Authors:Yang D, Forsmark CE
Institution:Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, Florida, USA.
Journal:Curr Opin Gastroenterol. 2017 Sep;33(5):396-403. doi: 10.1097/MOG.0000000000000377.

10:Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Authors:Kirkegard J, Mortensen FV, Cronin-Fenton D
Institution:Department of Surgery, HPB Section; Aarhus University Hospital, Aarhus, Denmark.
Journal:Am J Gastroenterol. 2017 Sep;112(9):1366-1372. doi: 10.1038/ajg.2017.218. Epub 2017 Aug 1.

11:Incidence of and risk factors for pancreatic cancer in chronic pancreatitis: A cohort of 1656 patients.
Authors:Hao L, Zeng XP, Xin L, Wang D, Pan J, Bi YW, Ji JT, Du TT, Lin JH, Zhang D, Ye B, Zou WB, Chen H, Xie T, Li BR, Zheng ZH, Wang T, Guo HL, Liao Z, Li ZS, Hu LH
Institution:Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China.; Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China; Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, Shanghai, China. Electronic address: zhaoshen-li@hotmail.com.; Department of surgery, Jinling Hospital, Nanjing, China.; Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, China.; Department of Gastroenterology, Air Force General Hospital, Beijing, China.
Journal:Dig Liver Dis. 2017 Nov;49(11):1249-1256. doi: 10.1016/j.dld.2017.07.001. Epub 2017 Jul 15.

12:Assessing the value of endoscopic ultrasound in predicting symptom severity and long-term clinical course in chronic pancreatitis.
Authors:Bhutiani N, Richey JS, Brown AN, Tierney J, McClave SA, Bahr MH, Vitale GC
Institution:Department of Surgery, University of Louisville, 550 S. Jackson Street, Louisville, KY, 40202, United States. Electronic address: garyvitale@gmail.com.; Department of Medicine, Division of Gastoenterology, University of Louisville, Louisville, KY, United States.
Journal:HPB (Oxford). 2017 Oct;19(10):868-873. doi: 10.1016/j.hpb.2017.05.012. Epub 2017 Jul 15.

13:Robotic longitudinal pancreaticojejunostomy for chronic pancreatitis: Comparison of clinical outcomes and cost to the open approach.
Authors:Kirks RC, Lorimer PD, Fruscione M, Cochran A, Baker EH, Iannitti DA, Vrochides D, Martinie JB
Institution:Division of Hepatopancreatobiliary Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA.; Division of Surgical Oncology, Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA.
Journal:Int J Med Robot. 2017 Sep;13(3). doi: 10.1002/rcs.1832. Epub 2017 May 26.

14:Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management.
Authors:Scheers I, Palermo JJ, Freedman S, Wilschanski M, Shah U, Abu-El-Haija M, Barth B, Fishman DS, Gariepy C, Giefer MJ, Heyman MB, Himes RW, Husain SZ, Lin TK, Liu Q, Lowe M, Mascarenhas M, Morinville V, Ooi CY, Perito ER, Piccoli DA, Pohl JF, Schwarzenberg SJ, Troendle D, Werlin S, Zimmerman B, Uc A, Gonska T
Institution:Hospital for Sick Children, Toronto, Ontario, Canada. Massachusetts, USA. Massachusetts, USA. Los Angeles, Los Angeles, California, USA. University of New South Wales and Sydney Children's Hospital Randwick, Sydney, New South Wales, Australia.
Journal:Am J Gastroenterol. 2017 Oct;112(10):1604-1611. doi: 10.1038/ajg.2017.85. Epub 2017 Apr 4.

15:Diagnostic performance of imaging modalities in chronic pancreatitis: a systematic review and meta-analysis.
Authors:Issa Y, Kempeneers MA, van Santvoort HC, Bollen TL, Bipat S, Boermeester MA
Institution:Department of Surgery, Academic Medical Centre, Meibergdreef 9, 1100DD, Amsterdam, The Netherlands. Amsterdam, The Netherlands. Amsterdam, The Netherlands. Nieuwegein, The Netherlands. Amsterdam, The Netherlands. Amsterdam, The Netherlands. m.a.boermeester@amc.uva.nl.
Journal:Eur Radiol. 2017 Sep;27(9):3820-3844. doi: 10.1007/s00330-016-4720-9. Epub 2017 Jan 27.

16:Outcomes After Conservative, Endoscopic, and Surgical Treatment of Groove Pancreatitis: A Systematic Review.
Authors:Kager LM, Lekkerkerker SJ, Arvanitakis M, Delhaye M, Fockens P, Boermeester MA, van Hooft JE, Besselink MG
Institution:*Department of Gastroenterology & Hepatology, Noordwest Ziekenhuisgroep, Alkmaar Departments of daggerGastroenterology & Hepatology section signSurgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands double daggerDepartment of Gastroenterology & Hepatology, Hepatopancreatology and GI Oncology, Erasme University Hospital, Universite Libre de Bruxelles, Brussels, Belgium.
Journal:J Clin Gastroenterol. 2017 Sep;51(8):749-754. doi: 10.1097/MCG.0000000000000746.

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"Thank you. Thank you. Thank you. I am a 37-year old man with chronic pancreatitis. I didn't know where to start looking for information about this condition on the Internet. Medifocus gave me a great start. The explanations of my illness were very comprehensive and now I can talk better with my doctor about my treatment options."
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